CUVITRU is indicated as replacement therapy for primary humoral immunodeficiency (PI) in adult and pediatric patients ≥2 years. CUVITRU is for subcutaneous use only.
The median duration of once-weekly infusions was <1 hour (0.95 hours; range: 0.2-6.4 hours) in the North American clinical study.
*If a patient is 75 kg (165 lb) and has been prescribed 36 g of IVIG per month, you could switch your patient to 12 g of CUVITRU weekly. After the first 2 infusions, subsequent infusions of CUVITRU could be completed in 15 minutes at a rate of 60 mL/h/site using 4 sites simultaneously.
†Infuse first 2 infusions at 10 to 20 mL/h/site.
84.9% (N=4314) of infusions were administered using only 1 or 2 infusion sites (18.5%=1 site; 66.4%=2 sites) in the North American clinical study.
SCIG=subcutaneous immune globulin.
To see important information for starting your patients on CUVITRU, explore the tabs below.
Use the infusion calculator to determine CUVITRU administration parameter combinations for your patients based on needlesticks and frequency of infusions, and help your patients achieve CUVITRU’s maximum infusion rate by selecting the proper supplies.
Choose from the following parameters to find the right dosing plan for you and your patient.
The dosing calculator is meant to be used as a tool to help HCPs make informed decisions about dosing. Takeda is not making dosing recommendations.
To determine the dosage ranges for a patient, select the weight closest to the patient’s weight in the window on the left. Dosage ranges will appear in grams. See Full Prescribing Information for additional dosage recommendations. A conversion factor of 2.2046 lb/kg is used to convert the patient’s weight to kilograms. The values displayed are rounded to the nearest decimal point.
What is the
Dosage range to be prescribed every 3-4 weeks or per patient needs
This calculator does not represent every possible weight calculation. Weights begin as 88 lb and increase in 4 lb increments to 288 lb.
CUVITRU is available in 1 g, 2 g, 4 g, 8 g, and 10 g vials of IG 20%. The dose must be rounded up or down, based on the physician’s clinical judgement.
View examples of 2 patients’ infusion sites from pre-infusion to 24 hours after.
Volume infused per physician guidance based on patient’s speciﬁc clinical condition. It may be different for other patients.
*1-hour infusion time.
Learn about starting patients on CUVITRU